Noonan Syndrome: PTPN11 and SOS1 Studies

We are looking for male and female participants, ages 5-11, with confirmed PTPN11 or SOS1 mutations for a research study looking at the relationship between the brain and behavior in Noonan syndrome. Study visits typically consist of two (6-8 hour) days.


Participants can earn $100 for completing all parts of the study.

Participation involves:

  • Cognitive and behavioral evaluations
  • Brain imaging with MRI. Scans are safe, non-invasive, and do not involve X-rays. They are primarily used to look at the structures of the brain. However, because MRIs involve magnets, we generally cannot include anyone with metal in their bodies, like braces or other metal implants.


Potential benefits of participating:

  • Information from research behavioral and cognitive assessment, with a research report of the assessment results
  • Flight/hotel/ground transportation costs covered for the participating child and one care-giver/parent


For more information, contact the study coordinator, Raul Barete, at or (650) 440-1902.

For further information regarding questions, concerns, or complaints about research, research related injury, and questions about the rights of research participants, please call (650) 723-5244 or call toll free 1-866-680-2906, or write the Administrative Panel on Human Subjects in Medical Research, Administrative Panels Office, Stanford University, Stanford, CA 94305-5401.