Depression and suicide in children and adolescents are major public health concerns. Major depressive disorder, a debilitating and potentially life-threatening disorder, has a 15% - 20% life time prevalence in adolescents, and is a major cause for suicide attempts in this age-group. The neural underpinnings of predisposition to depression and suicide are poorly understood.
The CIBSR is conducting a study investigating how brain pathways and brain function differ between adolescent females with depressive symptoms and adolescent females with no depressive symptoms. We also comparing brain pathways and function in depressed individuals with and without a history of psychological trauma, such as abuse. The goal of these studies are to identify brain regions that are affected in adolescent depression that could serve as future targets for treatment of the disorder.
For more information please visit the study website here